Since 1999 Hunter’s Hope has awarded millions of dollars in grants for research related to Krabbe Disease and other Leukodystrophies.
Mark Noble, Ph.D. – University of Rochester Stem Cell & Regenerative Medicine Institute – Rochester, NY
“Umbilical Cord Stem Cell Therapy for Krabbe’s disease: The problem of chemotherapy-mediated damage to the CNS”
Mark S. Sands, Ph.D. – Washington University School of Medicine – St. Louis, MO
“Combinatorial Therapies for Krabbe Disease”
David Archer, Ph.D. – Emory University School of Medicine – Atlanta, GA
“In Utero Therapy for Murine Glactosylceramidase Deficiency”
Gary Baskin, DVM – Tulane University Medical Center – Covington, LA
“Development of a Nonhuman Primate Model for Gene Therapy of Krabbe Disease”
Karin Blakemore, M.D. – John Hopkins University – Baltimore, MD
“A Canine Model for In Utero Bone Marrow Transplantation”
Bruce J. Brew, MBBS, MD, FRACP – University of New South Wales – Sydney, Australia
“Marrow Stromal Cell Transplantation for the Treatment of Krabbe Disease”
Bruce Bunnell, Ph.D. – Tulane University Health Sciences Center – New Orleans, LA
“Marrow Stromal Cell-Mediated Gene Therapy of Krabbe’s Disease in a Nonhuman Primate Model”
Timothy Cox, M.D. – University of Cambridge – Cambridge, England
“Therapeutic Gene Delivery for Cerebral Leukodystrophies Using Herpes Simplex Virus-based Vectors”
Ian Duncan, BVMS, Ph.D., FRC, VSFRCP – University of Wisconsin School of Veterinary Medicine – Madison, WI
“Inhibition of Globoid Cell-Microglial Function in the Twitcher Mouse; a Potential Therapy for Krabbe Disease?”
Isabelle Dusart, Ph.D. – INSERM ACS Paris IV Saint-Antoine – Paris, France
“Study of Factors that Favor Myelination: An In Vitro Model of Pelizaeus- Merzbacher”
Mary Eapen, M.D., M.S. – Medical College of Wisconsin IBMTR – Milwaukee, WI
“Outcomes After Hematopoietic Stem Cell Transplantation for Globoid Cell Leukodystrophy”
Christopher Eckman, Ph.D. – Mayo Clinic Jacksonville – Jacksonville, FL
“Protein Treatment for Krabbe Disease; a Feasibility Analysis of TAT PTD/GALC Fusion Proteins for Treatment”
Maria Luisa Escolar, M.D. – University of North Carolina at Chapel Hill – Chapel, Hill, NC
“Development of a Staging System for Infantile Krabbe’s Disease”
Corrine Fantz, Ph.D. – Washington University School of Medicine – St. Louis, MO
“Neonatal Gene Transfer for Treatment of Globoid Cell Leukodystrophy”
Miguel Gama Sosa, Ph.D. – Mt. Sinai School of Medicine – New York, NY
“Ex Vivo Gene Therapy of Krabbe Disease Genetic and Cellular Therapy of Krabbe Disease”
“Transgenic Rescue of Twitcher Mice”
Robert Gould, Ph.D. – NYS Institute for Basic Research – Staten Island, NY
“Myelin Genes Affected During Development of Krabbe Disease Symptoms in the Twitcher Mouse”
Dong-Soon Im, Ph.D. – University of Virginia – Charlottesville, VA
“Molecular Characterization of a Human Psychosine Receptor”
Joanne Kurtzberg, M.D. – Duke University Medical Center – Durham, NC
“Selection and Screening of Umbilical Cord Blood (UCB) for Stem Cell Transplantation in Krabbe Disease”
Paola Leone, Ph.D. – University of Medicine & Dent of NJ/Robert Wood Johnson Medical School – Camden, NJ
“Gene Therapy of a Rat Model of Leukodystrophy”
Steven LeVine, Ph.D. – University of Kansas Medical Center Research Institute – Kansas City, KS
“Therapeutic Interventions for Krabbe Disease”
“Modifier Genes in Krabbe Disease”
Paola Luzi, Ph.D. – Thomas Jefferson University – Philadelphia, PA
“SV40 Containing Galactocerebrosidase (GALC) Transgene: A Novel Gene Therapy Approach for the Treatment of Krabbe Disease”
Peter Meikle, Ph.D. – Women’s and Children’s Hospital – North Adelaide, Australia
“Newborn Screening, Patient Prognosis and Monitoring of Therapy for Krabbe Disease and Metachromatic Leukodystrophy”
The Myelin Project – Dunn Loring, VA
“Human Schwann Cell Transplantation Trial at Yale University”
Barbara Paton, Ph.D. – Women’s and Children’s Hospital, North Adelaide, South Australia
“Improving Peroxisomal Function in the Peroxisomal Biogenesis Defects”
Mohammad Rafi, Ph.D. – Jefferson Medical College – Philadelphia, PA
“Ex Vivo Gene Therapy for the Mouse Model of Globoid Cell Leukodystrophy Using Astrocytes and Marrow Stromal Cells”
Thiruvamoor Ramkumar, Ph.D. – Washington University – St. Louis, MO
“Multi-Lectin Receptors as Potential Targets for Krabbe Disease”
Evan Snyder, M.D., Ph.D. – Harvard Medical School/Harvard Institutes of Medicine – Boston, MA
“Neural Stem Cells as Vehicles for Globalcellular & Gene Therapy in Krabbe Globoid Cell Leukodystrophy”
Ramandeep Takhter, Ph.D. – Mayo Clinic Rochester – Rochester, MN
“Sphingolipid Endocytosis During Differentiation of Oligodendrocytes and its Role in Myelin Formation”
Phillip Whitfield, Ph.D. – Women’s & Children’s Hospital – North Adelaide, Australia
“Krabbe Disease: Newborn Screening, Improved Diagnosis and Monitoring Therapy”