Grants Awarded

Hunter's Hope has funded the following studies:

David Archer, Ph.D. - Emory University School of Medicine - Atlanta, GA
"In Utero Therapy for Murine Glactosylceramidase Deficiency"

Gary Baskin, DVM - Tulane University Medical Center - Covington, LA
"Development of a Nonhuman Primate Model for Gene Therapy of Krabbe Disease"

Karin Blakemore, M.D. - John Hopkins University - Baltimore, MD
"A Canine Model for In Utero Bone Marrow Transplantation"

Bruce J. Brew, MBBS, MD, FRACP - University of New South Wales - Sydney, Australia
"Marrow Stromal Cell Transplantation for the Treatment of Krabbe Disease"

Bruce Bunnell, Ph.D. - Tulane University Health Sciences Center - New Orleans, LA
"Marrow Stromal Cell-Mediated Gene Therapy of Krabbe's Disease in a Nonhuman Primate Model"

Timothy Cox, M.D. - University of Cambridge - Cambridge, England
"Therapeutic Gene Delivery for Cerebral Leukodystrophies Using Herpes Simplex Virus-based Vectors"

Ian Duncan, BVMS, Ph.D., FRC, VSFRCP - University of Wisconsin School of Veterinary Medicine - Madison, WI
"Inhibition of Globoid Cell-Microglial Function in the Twitcher Mouse; a Potential Therapy for Krabbe Disease?"

Isabelle Dusart, Ph.D. - INSERM ACS Paris IV Saint-Antoine - Paris, France
"Study of Factors that Favor Myelination: An In Vitro Model of Pelizaeus-Merzbacher"

Mary Eapen, M.D., M.S. - Medical College of Wisconsin IBMTR - Milwaukee, WI
"Outcomes After Hematopoietic Stem Cell Transplantation for Globoid Cell Leukodystrophy"

Christopher Eckman, Ph.D. - Mayo Clinic Jacksonville - Jacksonville, FL
"Protein Treatment for Krabbe Disease; a Feasibility Analysis of TAT PTD/GALC Fusion Proteins for Treatment"

Maria Luisa Escolar, M.D. - University of North Carolina at Chapel Hill - Chapel, Hill, NC
"Development of a Staging System for Infantile Krabbe's Disease"

Corrine Fantz, Ph.D. - Washington University School of Medicine - St. Louis, MO
"Neonatal Gene Transfer for Treatment of Globoid Cell Leukodystrophy"

Miguel Gama Sosa, Ph.D. - Mt. Sinai School of Medicine - New York, NY
"Ex Vivo Gene Therapy of Krabbe Disease Genetic and Cellular Therapy of Krabbe Disease"
"Transgenic Rescue of Twitcher Mice"

Robert Gould, Ph.D. - NYS Institute for Basic Research - Staten Island, NY
"Myelin Genes Affected During Development of Krabbe Disease Symptoms in the Twitcher Mouse"

Dong-Soon Im, Ph.D. - University of Virginia - Charlottesville, VA
"Molecular Characterization of a Human Psychosine Receptor"

Joanne Kurtzberg, M.D. - Duke University Medical Center - Durham, NC
"Selection and Screening of Umbilical Cord Blood (UCB) for Stem Cell Transplantation in Krabbe Disease"

Paola Leone, Ph.D. - University of Medicine & Dent of NJ/Robert Wood Johnson Medical School- Camden, NJ
"Gene Therapy of a Rat Model of Leukodystrophy"

Steven LeVine, Ph.D. - University of Kansas Medical Center Research Institute - Kansas City, KS
"Therapeutic Interventions for Krabbe Disease"
"Modifier Genes in Krabbe Disease"

Paola Luzi, Ph.D. - Thomas Jefferson University - Philadelphia, PA
"SV40 Containing Galactocerebrosidase (GALC) Transgene: A Novel Gene Therapy Approach for the Treatment of Krabbe Disease"

Peter Meikle, Ph.D. - Women's and Children's Hospital - North Adelaide, Australia
"Newborn Screening, Patient Prognosis and Monitoring of Therapy for Krabbe Disease and Metachromatic Leukodystrophy"

The Myelin Project - Dunn Loring, VA
"Human Schwann Cell Transplantation Trial at Yale University"

Barbara Paton, Ph.D. - Women's and Children's Hospital, North Adelaide, South Australia
"Improving Peroxisomal Function in the Peroxisomal Biogenesis Defects"

Mohammad Rafi, Ph.D. - Jefferson Medical College - Philadelphia, PA
"Ex Vivo Gene Therapy for the Mouse Model of Globoid Cell Leukodystrophy Using Astrocytes and Marrow Stromal Cells"

Thiruvamoor Ramkumar, Ph.D. - Washington University - St. Louis, MO
"Multi-Lectin Receptors as Potential Targets for Krabbe Disease"

Evan Snyder, M.D., Ph.D. - Harvard Medical School/Harvard Institutes of Medicine - Boston, MA
"Neural Stem Cells as Vehicles for Globalcellular & Gene Therapy in Krabbe Globoid Cell Leukodystrophy"

Ramandeep Takhter, Ph.D. - Mayo Clinic Rochester - Rochester, MN
"Sphingolipid Endocytosis During Differentiation of Oligodendrocytes and its Role in Myelin Formation"

Phillip Whitfield, Ph.D. - Women's & Children's Hospital - North Adelaide, Australia
"Krabbe Disease: Newborn Screening, Improved Diagnosis and Monitoring Therapy"