The Hunter James Kelly Research Institute

Since 1999 Hunter's Hope has awarded over $4 million in grants for research related to Krabbe Disease and other Leukodystrophies. Recently the Foundation has partnered with the University of Buffalo to establish the Hunter James Kelly Research Institute (HJKRI). Because of this new research initiative, Hunter's Hope is holding off on funding new grant applications at this time. Any applications that we have received up to June 2004, will be reviewed for potential funding. Further information on this will be available on our website as it becomes available.

What is Hunter James Kelly Research Institute?
The Hunter James Kelly Research Institute (HJKRI) is a partnership between UB and the Hunter’s Hope Foundation. The HJKRI will be located in downtown Buffalo, New York, in the New York State Center for Excellence in Bioinformatics and Life Sciences at the University at Buffalo. The NYS Center of Excellence is part of the Buffalo Life Science Complex.

All Hunter’s Hope funded research will be coordinated through the HJKRI. This includes research that will be conducted at the Institute (“intramural”) as well as research conducted at other locations (“extramural”). The “intramural” research will be dedicated toward studying remyelination techniques, while the “extramural” research will focus on studying the biology and pathophysiology of Krabbe’s Disease, which should lead to the development of effective treatment strategies. This approach will allow both correction of the genetic defect as well as repair of the already damaged brain, providing a total solution for children with Krabbe’s Disease. In addition, research on remyelination techniques will not only help children with Krabbe’s and other leukodystrophies, but also patients with Multiple Sclerosis, stroke, and other diseases in which there is white matter destruction of the brain.

Buffalo Life Science Complex
The Buffalo Life Science Complex (BLSC) is a collaborative effort of Roswell Park Cancer Institute, the University at Buffalo, and the Hauptman-Woodward Medical Research Institute. The new complex builds on long-standing academic and research collaborations among the partners by physically linking the facilities and allowing for shared core research laboratories. While each of these structures will house distinctly different research functions, the work is synergistic and represents a continuum in the development of new therapeutics and diagnostics for a wide range of diseases.

Together the science and resources contained in the BLSC represent an enviable collection of intellectual and technical capacity that has the potential to propel Buffalo Niagara to the forefront of the country’s burgeoning life sciences industry.

• Hauptman-Woodward Medical Research Institute Structural Biology Research Center
• New York State Center for Excellence in Bioinformatics and Life Sciences at the University at Buffalo
• Roswell Park Cancer Institute Center for Genetics and Pharmacology

New York State Center for Excellence in Bioinformatics And Life Sciences at UB
Bioinformatics is the key research tool for realizing practical benefits, such as the development of new drugs and new drug therapies, from genome mapping.

At the Buffalo Center of Excellence in Bioinformatics, the merger of high-performance computing and high-end visualization, genomics, proteomics, and bioimaging is a unique and powerful combination of technologies and research expertise, enabling the center to make critical contributions to science and health care in the twenty-first century.

The University of Buffalo, Roswell Park Cancer Institute, the Hauptman-Woodward Medical Research Institute, and the State of New York are the center’s founding partners. Hunter’s Hope is a new partner.

Thank you for your patience and consideration. Much success has come from our funded research and we look forward to continuing that success.